The Lecturers
Glenn Howerton as Dr. Jack Griffin
A.P. Bio may be very a lot designed as a showcase for TV comedy heavy hitter Glenn Howerton. Previous to (and certainly concurrently with and after) his position as Jack Griffin, Howerton was finest identified for portraying Dennis Reynolds on long-running FX comedy It’s All the time Sunny in Philadelphia. Happening 20 years, Howerton’s performances because the borderline sociopathic Dennis has been a comedic masterclass. Now viewers have gotten to know him just a little higher by way of The All the time Sunny Podcast and his award-winning position as Blackberry co-founder Jim Balsillie in 2023’s Blackberry.
Lyric Lewis as Stef Duncan
Stef Duncan is a historical past instructor at Whitlock Excessive College and a part of the unshakeable Stef-Mary-Michelle friendship trio. Enjoying her is Lyric Lewis, who has beforehand appeared in TV comedies Baskets, iCarly, and Celebration Down.
Mary Sohn as Mary Wagner
Mary is an artwork instructor at Whitlock Excessive College and a part of the aforementioned Stef-Mary-Michelle friendship trio. Enjoying her is Mary Sohn, a comedic actress who has appeared in Miracle Staff, Between Two Ferns: The Movie, and Curb Your Enthusiasm. She has additionally made a number of appearances voicing characters on the Comedy Bang! Bang! podcast.
Jean Villepique as Michelle Jones
Michelle Jones is the house economics instructor at Whitlock Excessive College and is the oddball spoke of the Stef-Mary-Michelle friendship trio. Jean Villepique has popped up in quite a few comedy collection since 2007, together with The Workplace, Trendy Household, and Veep. Shortly earlier than A.P. Bio, she voiced adoption caseworker Tracy in BoJack Horseman.
Patton Oswalt as Principal Ralph Durbin
Principal Ralph Durbin is the overmatched chief of Whitlock Excessive College and the closest factor Jack Griffin has to a “buddy.” Enjoying Durbin is the prolific comedy legend Patton Oswalt, who has been in … simply, every part. Along with his long-running profession as a standup comedian and actor, Oswalt is understood to younger audiences because the voice of Remy in Pixar’s Ratatouille.
Paula Pell as Helen Henry Demarcus
The superbly-named Helen Henry Demarcus is Principal Durbin’s secretary who views him as one thing resembling her husband, son, finest buddy, and platonic soulmate. Enjoying Helen is comedic secret weapon Paula Pell. A revered author at Saturday Evening Reside from 1995 via 2020, Pell has moved in entrance of the digital camera extra lately, taking part in outstanding roles in Parks and Recreation, Documentary Now!, and Girls5eva.
